Qalabka Tijaabada Degdegga ah ee Kahortagga Jirka ee ka hortagga COVID-19 (Dahab Colloidal)

Qalabka Tijaabada Degdegga ah ee Kahortagga-Dhexdhexaadinta COVID-19 (Dahab Dahab ah) Sawirka sifaysan

Sharaxaad Gaaban:

Faahfaahinta Alaabta

Isticmaalka damacsan:

◆Si loo ogaado unugyada difaaca jirka.

◆COVID-19 Dhexdhexaadinta Qalabka Tijaabada Degdegga ah ee Kahortagga Jirka (Colloidal Gold) waa tallaalka qulqulka dambe ee immunoassay loogu talagalay ogaanshaha tayada leh ee ka takhalusidda antibody-ka SARS-CoV-2 ee dhiigga bini'aadamka oo dhan, serum ama Plasma si gargaar loogu helo heerarka qiimeynta ee ka hortagga aadanaha - novel coronavirus ka takhalusaya titer antibody.

Habka saamiga

◆Dhiigga oo dhan, Serum, Plasma

Mabda'a Shaqada:

◆Qalabkani waxa uu isticmaalaa immunochromatography.Kaadhka imtixaanku waxa uu ka kooban yahay:1) recombinant novel coronavirus S-RBD antigen iyo calamadaha dahabka ka hortagga tayada;2) Hal xariiq ogaanshaha (T line) iyo hal xariiqa xakamaynta tayada (C line) ee xuubka nitrocellulose.Khadka T waxa lagu dhaqaajiyaa borotiinka Human ACE2 si loo ogaado coronavirus-ka cusub ee ka takhalusaya antibody-ka iyo khadka C waxa lagu dhaqaaqi karaa iyada oo leh antibody-ka-hortagga tayada.

◆Marka qadar ku habboon muunadda tijaabada lagu daro daloolka muunadda ee kaadhka tijaabada, muunada ayaa hore ugu sii socon doonta kaadhka tijaabada iyada oo la raacayo ficilka xididka.Haddii shaybaarku ka kooban yahay novel coronavirus neutralizing antibody, antibody-ga ayaa ku xidhi doona novel coronavirus antigen-ka kolloidal-dahab ah.Inta soo hartay ee ku suntan novel coronavirus antigen-ka cusub ee dahabka leh ee ku jira dhismaha difaaca waxaa qabsan doona borotiinka ACE2 ee bini'aadamka ee aan dhaqdhaqaaq lahayn

xuubka si uu u sameeyo xariiq T- guduudan-cas ah, xoojinta xariiqda t Si ka duwan u dhiganta fiirsashada antibody.

◆Kaarka imtixaanku waxa kale oo uu ka kooban yahay xariiqda xakamaynta tayada C .Xadhka xakamaynta tayada fuchsia C waa in uu soo muuqdaa iyada oo aan loo eegin in xariiqda imtixaanku soo baxayo.Haddii xariiqda xakamaynta tayada C uusan soo bixin, natiijadu waa mid aan sax ahayn, muunaddana waxay u baahan tahay in mar kale lagu tijaabiyo kaadh kale oo tijaabo ah.

Faahfaahinta alaabta:

Cudurka neef-mareenka ee daran ee coronavirus 2 (SARS-CoV-2, ama 2019-nCoV) waa fayraska RNA ee dareenka togan ee aan qaybsanayn.Waa ka

sababta COVID-19, kaas oo la kala qaado dadka.

◆SARS-CoV-2 waxay leedahay borotiinno dhismeed dhowr ah oo ay ku jiraan spike (S), baqshadda (E), xuubka (M) iyo nucleocapsid (N).Borotiinka spike (S) waxa ku jira aagga xidhidhiyaha reseptor-ka (RBD), kaas oo mas'uul ka ah aqoonsiga soo-dhoweeyaha unugga, antigens beddelaadda enzyme-2 (ACE2).Waxaa laga helaa uman ACE2 reseptor u horseedaysa endocytosis galay unugyada martida loo yahay ee sambabada qoto dheer iyo taranka fayraska.

◆Infekshanka SARS-CoV-2 ama SARS-COV-2 Tallaalka wuxuu bilaabaa jawaab-celin difaac si loo soo saaro unugyada difaaca jirka kuwaas oo ka ilaalinaya caabuqyada mustaqbalka ee fayraska.Ka-hortagga ka-hortagga bini-aadmiga ee bar-tilmaameedsada martigeliyaha ACE2 receptor-binding domain (RBD) ee borotiinka SAR-COV-2 wuxuu muujinayaa ballanqaad daweyn iyo hufnaan ilaalin leh.

◆ Dhiiga caarada faraha ee serum ama balasmaha.

◆Si loo ogaado nus-tiro-tiro ah ee ka-hortagga ka-hortagga.

◆ Dhexdhexaadinta ka hortagga unugyada waxay ogaan kartaa inay jiraan unugyada difaaca jirka ee ka soo horjeeda SARS-CoV-2 ee jirka.

◆Ka caawi la socoshada cimriga dheer ee difaaca jirka tallaalka ka dib.